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Water Importance and Pollution Sources—Recommended Limits of Pollutants

There are many water resources like rivers, seas, rains, and groundwater, which can be used in different sectors such as agricultural, domestic, and industrial uses. Therefore, different wastewater effluents with different properties are produced depending on their source. Industrial wastewater is one of the most harmful effluents due to the presence of toxic pollutants such as heavy metals, dyes, and other toxic substances. Usually, water is used in different industries for different internal processes, and then the resulting wastewater is discharged without treatment into the water resources
Healthcare
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Detection and Identification of Adulteration in Vinegar Samples Based on Reversed-Phase High-Performance Liquid Chromatographic (RP-HPLC) Strategies

Adulteration of vinegar to gain economic benefit has become a common practice in recent years. RP-HPLC strategies were proposed for the assurance of the concentration of acetic acid, rare organic acids (tartaric, malic, lactic and citric), and acetaldehyde in Egyptian vinegar samples. The flow rate was 0.5 mL/min using UV detection at 210 and 365 nm for organic acid and acetaldehyde, respectively. The linearity was 0.05-0.60 g/100 mL for acetic acid, 0.01-0.12 g/100 mL for citric, malic, and tartaric acids, 0.005-0.060 g/100 mL for lactic acid, and 0.02-0.16 mg/L for acetaldehyde with r2 > 0
Healthcare
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Citric acid assisted phytoextraction of nickle from soil helps to tolerate oxidative stress and expression profile of NRAMP genes in sunflower at different growth stages

Soil polluted with Nickel (Ni) adversely affects sunflower growth resulting in reduced yield. Counterbalancing Ni toxicity requires complex molecular, biochemical, and physiological mechanisms at the cellular, tissue, and whole plant levels, which might improve crop productivity. One of the primary adaptations to tolerate Ni toxicity is the enhanced production of antioxidant enzymes and the elevated expression of Ni responsive genes. Methods: In this study, biochemical parameters, production of ROS, antioxidants regulation, and expression of NRAMP metal transporter genes were studied under Ni
Healthcare
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Genome-wide comparison and identification of myosin gene family in Arabidopsis thaliana and Helianthus annuus

Myosins are essential components of organelle trafficking in all the eukaryotic cells. Myosin driven movement plays a vital role in the development of pollen tubes, root hairs and root tips of flowering plants. The present research characterized the myosin genes in Arabidopsis thaliana and Helianthus annuus by using different computational tools. We discovered a total of 50 myosin genes and their splice variants in both pant species. Phylogenetic analysis indicated that myosin genes were divided into four subclasses. Chromosomal location revealed that myosin genes were located on all five
Healthcare
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Biochemical and genotyping analyses of camels (Camelus dromedaries) trypanosomiasis in North Africa

Camels are considered an important food source in North Africa. Trypanosomiasis in camels is a life-threatening disease that causes severe economic losses in milk and meat production. Therefore, the objective of this study was to determine the trypanosome genotypes in the North African region. Trypanosome infection rates were determined by microscopic examination of blood smears and polymerase chain reaction (PCR). In addition, total antioxidant capacity (TAC), lipid peroxides (MDA), reduced glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT) were determined in erythrocyte lysate
Healthcare

Phylogeographic and population genetic structure of hound-like native dogs of the Mediterranean Basin

The dog was probably the first domesticated animal. Despite extensive archaeological and genetic investigations, the origin and the evolution of the extant dogs are still being debated. Dog breeds that have over time been selected for hunting share common ancestral traits. This study represents the first comprehensive attempt to survey at the genomic and mitochondrial level eight hound-like dogs breeds indigenous to the Mediterranean Basin to determine if they share common ancient origins. Results from the microsatellite analysis indicate that all the dog populations have a low inbreeding
Healthcare

Can Micro RNA-24 Affect the Cardiovascular Morbidity in Systemic Lupus Erythematosus by Targeting YKL-40?

Systemic lupus erythematosus (SLE) is an autoimmune disease with inflammatory nature. One of the leading causes of death in SLE patients is cardiovascular (CVS) morbidity. MiRNA-24 is highly expressed in vascular endothelial cells (VECs). This dysregulated expression pattern is associated with dysfunction or even damage of VECs and leads to the occurrence of cardiovascular diseases. YKL-40 is an inflammatory glycoprotein involved in the pathogenesis of endothelial dysfunction and thereby atherosclerosis. In this work, we aimed at illustrating the possible role of miR-24 and its target YKL-40
Healthcare
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Prognostic significance of the genetic variant of lymphotoxin alpha (p.Thr60Asn) in egyptian patients with advanced hepatocellular carcinoma

Background: Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide in terms of mortality, and susceptibility is attributed to genetic, lifestyle, and environmental factors. Lymphotoxin alpha (LTA) has a crucial role in communicating the lymphocytes with stromal cells and provoking cytotoxic effects on the cancer cells. There are no reports on the contribution of the LTA (c.179 C>A; p.Thr60Asn; rs1041981) gene polymorphism to HCC susceptibility. The main aim of this study is to investigate the association of LTA (c.179 C>A; p.Thr60Asn; rs1041981) variant with the HCC
Healthcare

Molecular identification of extended spectrum β-lactamases (ESBLs)-producing strains in clinical specimens from Tiruchirappalli, India

Worldwide, the phenomenal antimicrobial resistance with its consequences of fatal diseases has been alerted; it is because the morbidity and mortality at a shocking rate. Therefore, there is an urgent quest of innovative antimicrobials agents; it is that communicable disease is a worldwide trouble as of the growth and wideness of drug-resistant pathogens. As for the aim of the research, it is widely investigative to the prevalence of Gram-negative pathogens of E. coli and K. pneumoniae in different age groups, gender along with the identification of ESBL-producing pathogens and antimicrobial

Healthcare

Nanomaterial-based drug delivery systems as promising carriers for patients with COVID-19

Once the World Health Organization (WHO) declared the COVID-19 outbreak to be pandemic, massive efforts have been launched by researchers around the globe to combat this emerging infectious disease. Here we review the most recent data on the novel SARS-CoV-2 pathogen. We analyzed its etiology, pathogenesis, diagnosis, prevention, and current medications. After that, we summarized the promising drug delivery application of nanomaterial-based systems. Their preparation routes, unique advantages over the traditional drug delivery routes and their toxicity though risk analysis were also covered

Healthcare
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