Stimulated echo acquisition mode (STEAM) is a generic imaging technique that lies at the core of many magnetic resonance imaging (MRI) techniques such MRI tagging, displacement encoded MRI, black-blood cardiac imaging. Nevertheless, tissue deformation causes frequency shift of the MR signal and leads to severe signal attenuation. In this work, a maximum likelihood estimator for the signal amplitude is proposed and used to correct the image artifacts. Numerical simulation and real MR data are used to test and validate the proposed method. © 2011 IEEE.

In the last few years the gene expression microarray technology has become a central tool in the field of functional genomics in which the expression levels of thousands of genes in a biological sample are determined in a single experiment. Several clustering and biclustering methods have been introduced to analyze the gene expression data by identifying the similar patterns and grouping genes into subsets that share biological significance. However, it is not clear how the different methods compare with each other with respect to the biological relevance of the biclusters and clusters as well

Clusters of microcalcifications in mammograms are an important early sign of breast cancer in women. Comparing with microcalcifications, the breast background tissues have high local self-similarity, which is the basic property of fractal objects. A fast fractal modeling method of mammograms for detecting the presence of microcalcifications is proposed in this paper. The conventional fractal modeling method consumes too much computation time. In the proposed method, the image is divided into shade (homogeneous) and non-shade blocks based on the dynamic range and only the non-shade blocks are

We propose an Automatic Gene Ontology (AGO) software as a flexible, open-source Matlab software tool that allows the user to easily compare the results of the bicluster and cluster methods. This software provides several methods to differentiate and compare the results of candidate algorithms. The results reveal that bicluster/cluster algorithms could be considered as integrated modules to recover the interesting patterns in the microarray datasets. The further application of AGO could to solve the dimensionality reduction of the gene regulatory networks. Availability: AGO and help file is

The contribution of this paper is twofold. First, we provide new theoretical insights into the relationship between a string and its reverse: If the Burrows-Wheeler transform (BWT) of a string has been computed by sorting its suffixes, then the BWT and the longest common prefix array of the reverse string can be derived from it without suffix sorting. Furthermore, we show that the longest common prefix arrays of a string and its reverse are permutations of each other. Second, we provide a parallel algorithm that, given the BWT of a string, computes the BWT of its reverse much faster than all

Image denoising is of paramount importance in image processing. In this paper, we propose a new design technique for the design of Double density Discrete Wavelet Transform (DD DWT) AND DD CWT filter bank structure. These filter banks satisfy the perfect reconstruction as well as alias free properties of the DWT. Next, we utilized this filter bank structure in image denoising. Our denoising scheme is based on utilizing the interscale correlation/interscale dependence between wavelet coefficients of a DD DWT of the noisy image. This is known as the Bivariate Shrinkage scheme. More precisely, we

Cloud computing provides a promising solution to the big data problem associated with next generation sequencing applications. The increasing number of cloud service providers, who compete in terms of performance and price, is a clear indication of a growing market with high demand. However, current cloud computing based applications in bioinformatics do not profit from this progress, because they are still limited to just one cloud service provider. In this paper, we present different use case scenarios using hybrid services and resources from multiple cloud providers for bioinformatics

In the era of digital transformation, a mass disruption in the global industries have been detected. Big data, the Internet of Things (IoT) and Artificial Intelligence (AI) are just examples of technologies that are holding such digital disruptive power. On the other hand, retailing is a high-intensity competition and disruptive industry driving the global economy and the second largest globally in employment after the agriculture. AI has large potential to contribute to global economic activity and the biggest sector gains would be in retail. AI is the engine that is poised to drive the

Multi-slice short-axis acquisitions of the left ventricle are fundamental for estimating the volume and mass of the left ventricle in cardiac MRI scans. Manual segmentation of the myocardium in all time frames per each cross-section is a cumbersome task. Therefore, automatic myocardium segmentation methods are essential for cardiac functional analysis. Region growing has been proposed to segment the myocardium. Although the technique is simple and fast, non uniform intensity and low-contrast interfaces of the myocardium are major challenges of the technique that limit its use in myocardial

Membrane computing is a computational framework that depends on the behavior and structure of living cells. P systems are arising from the biological processes which occur in the living cells’ organelles in a non-deterministic and maximally parallel manner. This paper aims to build a powerful computational model that combines the rules of active and mobile membranes, called Mutual Dynamic Membranes (MDM). The proposed model will describe the biological mechanisms of the metabolic regulation of mitochondrial dynamics made by mitochondrial membranes. The behaviors of the proposed model regulate