Diabetes is a common chronic metabolic disease with a wide range of clinical symptoms and consequences and one of the main causes of death. For the management of diabetes, painless and continuous interstitial fluid (ISF) glucose monitoring is ideal. Here, we demonstrate continuous diabetes monitoring using an integrated microneedle (MN) biosensor with an emergency alert system. MNs are a novel technique in the field of biomedical engineering because of their ability to analyze bioinformation with minimal invasion. In this work we developed a poly(methyl methacrylate) (PMMA) based MN glucose

Water contamination with paints causes a colour agent to the water that negatively affects the environment, organisms, and humans. Different physicochemical processes are applied for wastewater treatment; however, they have many drawbacks such as high cost, generating toxic waste, and non-effective at low concentrations. Adsorption is considered a promising technique for pollutant removal from polluted wastewater. Commercial activated carbon, nano-materials, and natural biological materials are used as adsorbents in adsorption. This chapter focuses on discussing the adsorption process, the

Gallbladder cancer (GBC) is an aggressive and lethal malignancy with a poor prognosis. Long noncoding RNAs (lncRNAs) and natural products have emerged as key orchestrators of cancer pathogenesis through widespread dysregulation across GBC transcriptomes. Functional studies have revealed that lncRNAs interact with oncoproteins and tumor suppressors to control proliferation, invasion, metastasis, angiogenesis, stemness, and drug resistance. Curcumin, baicalein, oleanolic acid, shikonin, oxymatrine, arctigenin, liensinine, fangchinoline, and dioscin are a few examples of natural compounds that

Aim The aim of this research was to study serum vitamin D and micro-ribonucleic acid-146a (miRNA-146a) expression in dry eye disease (DED) associated with rheumatoid arthritis (RA) and their clinical correlations to DED parameters. Setting and design This is an observational cross-sectional study that was conducted at Cairo University, Cairo, Egypt. Patients and methods The study participants were divided into three groups: group A, DED/RA (n=35); group B, non-DED/RA (n=36); and group C, non-DED/non-RA (n=35). All participants were assessed for ocular surface disease index, tear breakup time

Myosins are essential components of organelle trafficking in all the eukaryotic cells. Myosin driven movement plays a vital role in the development of pollen tubes, root hairs and root tips of flowering plants. The present research characterized the myosin genes in Arabidopsis thaliana and Helianthus annuus by using different computational tools. We discovered a total of 50 myosin genes and their splice variants in both pant species. Phylogenetic analysis indicated that myosin genes were divided into four subclasses. Chromosomal location revealed that myosin genes were located on all five

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Various thermodynamic quantities for baryon-free matter are calculated by combining the most reliable non-perturbative and perturbative calculations, especially the most recent ones including as many quark flavors as possible. We extend these calculations by including other degrees of freedom (dof), such as photons, neutrinos, leptons, electroweak particles and Higgs bosons, which allows us to consider temperatures up to the TeV-scale. The calculations show that similar to QCD, the EW phase transition is also a crossover. We have found that while the equation of state for the hadronic matter

Inflatable structures are characterized by being light and easy to manufacture and deploy. Hence, they find many applications in aerospace and aeronautical engineering. In this paper, an inflatable segment with a The National Advisory Committee for Aeronautics (NACA) 0021 airfoil cross-section is designed, fabricated, and tested. The geometrical accuracy of the manufactured inflatable segment is measured using laser scanning. Measurements show that the average normalized error of the chord length and thickness are 2.97% and 0.554%, respectively. The aerodynamic behavior of the inflatable

Doubly Fed Induction Generator (DFIG) based on wind turbines demand a high degree of reliability and availability and they are characterized by expensive and safety critical maintenance work. This paper deals with a new strategy for detection and estimation of current sensor faults in the stator and rotor of a DFIG. First, a state space model of a DFIG is developed based on voltages and flux equations, which can be used in order to estimate states and to generate residuals by using a Luenberger observer. Then, the residuals results are exploited for faults detection and estimation. Finally

Complex systems are pervasive in many areas of science. With the increasing requirement for high levels of system performance, complex systems has become an important area of research due to its role in many industries. Advances in System Dynamics and Control provides emerging research on the applications in the field of control and analysis for complex systems, with a special emphasis on how to solve various control design and observer design problems, nonlinear systems, interconnected systems, and singular systems. Featuring coverage on a broad range of topics, such as adaptive control