Genome-wide identification, phylogeny and expression analysis of the R2R3-MYB gene family in quinoa (Chenopodium quinoa) under abiotic stress
The MYB transcription factor (TF) are among the largest gene families of plants being responsible for several biological processes. The R2R3-MYB gene family are integral player regulating plant primary and secondary metabolism, growth and development, and responses to hormones and stresses. The phylogenetic analysis combined with gene structure analysis and motif determination resulted in division of R2R3-MYB gene family into 27 subgroups. Evidence generated from synteny analyses indicated that CqR2R3-MYBs gene family is featured by tandem and segmental duplication events. On the basis of RNA
Systems Thinking for Planning Sustainable Desert Agriculture Systems with Saline Groundwater Irrigation: A Review
Agricultural land expansion is a solution to address global food security challenges in the context of climate change. However, the sustainability of expansion in arid countries is difficult because of scarce surface water resources, groundwater salinity, and the health of salt-affected soil. Developing expansion and sustainability plans for agriculture requires systems thinking, considering the complex feedback interactions between saline groundwater, salt-affected soil, plant growth, freshwater mixing with saline groundwater, irrigation systems, and the application of soil amendments to
Can Micro RNA-24 Affect the Cardiovascular Morbidity in Systemic Lupus Erythematosus by Targeting YKL-40?
Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with inflammatory nature. One of the leading causes of death in SLE patients is cardiovascular (CVS) morbidity. MiRNA-24 is highly expressed in vascular endothelial cells (VECs). This dysregulated expression pattern is associated with dysfunction or even damage of VECs and leads to the occurrence of cardiovascular diseases. YKL-40 is an inflammatory glycoprotein involved in the pathogenesis of endothelial dysfunction and thereby atherosclerosis. In this work, we aimed at illustrating the possible role of miR-24 and its
Synergism between Saccharomyces cerevisiae probiotic and rosemary nano-emulsion: Effect on broiler chicken meat quality and shelf life
Although several studies have investigated the effect of either probiotic feed additives or postmortem meat treatment on the quality of obtained chicken meat, the impact of combined treatment with probiotic feed additives along with meat dipping in essential oil nano-emulsion on meat shelf-life is barely examined. There-fore, this study investigated the effect of combined treatment with Saccharomyces cerevisiae yeast (SCY) and rosemary oil nano-emulsion (RNE) on the quality and shelf-life of chilled broiler meat. The experimental part consisted of adding SCY as a feed additive to broiler
Integrated Analysis of Bulk and Single-Cell Transcriptomics in Cervical Cancer: Insights into BPGM, EGLN3, and SUN1
Cervical cancer (CC) is considered a significant global health threat to women therefore there is a need for personalized treatment strategy based on individual-specific gene expression patterns to enhance recovery and survival rates. Although a few studies have linked bisphosphoglycerate mutase (BPGM) expression with CC, its precise role in CC progression remains unclear. In this study, we conducted an integrated analysis for both bulk and single-cell RNA sequencing data to investigate the involvement of BPGM in CC. On the bulk RNA level, the Wilcoxon test result showed a significant
Prognostic significance of the genetic variant of lymphotoxin alpha (p.Thr60Asn) in egyptian patients with advanced hepatocellular carcinoma
Background: Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide in terms of mortality, and susceptibility is attributed to genetic, lifestyle, and environmental factors. Lymphotoxin alpha (LTA) has a crucial role in communicating the lymphocytes with stromal cells and provoking cytotoxic effects on the cancer cells. There are no reports on the contribution of the LTA (c.179 C>A; p.Thr60Asn; rs1041981) gene polymorphism to HCC susceptibility. The main aim of this study is to investigate the association of LTA (c.179 C>A; p.Thr60Asn; rs1041981) variant with the HCC
Water Importance and Pollution Sources—Recommended Limits of Pollutants
Biochemical and genotyping analyses of camels (Camelus dromedaries) trypanosomiasis in North Africa
Fabrication of Ultra-Pure Anisotropic Zinc Oxide Nanoparticles via Simple and Cost-Effective Route: Implications for UTI and EAC Medications
The purposes of this work are to evaluate the antimicrobial, antibiofilm, anticancer, and antioxidant abilities of anisotropic zinc oxide nanoparticles (ZnO NPs) synthesized by a cost-effective and eco-friendly sol–gel method. The synthesized ZnO NPs were entirely characterized by UV-Vis, XRD, FTIR, HRTEM, zeta potential, SEM mapping, BET surface analyzer, and EDX elemental analysis. Antimicrobial and antibiofilm activities of ZnO NPs were investigated against multidrug-resistant (MDR) bacteria and yeast causing serious diseases like urinary tract infection (UTI). The anticancer activity was
Simple implementations of fractional-order driving-point impedances: Application to biological tissue models
A novel procedure for the circuit implementation of the driving-point impedance of frequency-domain material models, constructed from fractional-order elements of arbitrary type and order, is introduced in this work. Following this newly introduced concept, instead of emulating separately each fractional-order element in the model under consideration, the direct emulation of the complete model can be achieved through the approximation of the total impedance function. The magnitude and phase frequency responses of the impedance function are first extracted and approximated through curve-fitting
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