Biomedical applications of nanomaterials have received considerable attention and interest from many researchers over the past decade due to the key role they can play in enhancing public health. Different types of nanomaterials possess both diagnostic and therapeutic potential owing to their outstanding properties compared to their bulk counterparts. Herein, we present, analyze and provide significant insights and recent advances about the promising biomedical applications of nanoparticles including bioimaging of biological environments and its role as a significant tool for early detection

Treatment of burn wounds has many requirements to ensure wound closure with healthy tissue, increased vascularization, guarantee edema resolution, and control bacterial infection. We propose that titanium oxide (TiO2) nanoparticles (NPs) will be more efficient than silver dioxide (Ag2O) in the treatment of burn wounds. Herein, gelatin loaded NPs (GLT-NPs) were evaluated for their efficacy to regenerate second-degree burn wound in rabbit skin. TEM results revealed that the average particle sizes were ⁓ 7.5 and 17 nm for Ag2O and TiO2 NPs, respectively. The results of the in vivo application of

Magnesium oxide (MgO) nanoparticles are one of the highly significant compounds in construction. The novelty concentrated on using sol–gel technique coupled with ultrasonication for synthesis of MgO nanoparticles to prevent the agglomeration and its effect on the size was investigated. The synthesized samples were characterized by TGA, DSC, XRD, FTIR, SEM, EDX mapping, DLS, and HRTEM. Antimicrobial and antibiofilm activities of MgO nanoparticles were investigated against multidrug-resistant microbes causing-urinary tract infection (UTI). TGA, XRD, and FTIR characterization were used to

Silver nanoparticles (AgNPs) have been extensively used in various industries; however, this is accompanied by several implications to humans and the environment. This review focuses on different aspects of AgNPs including the production and detection techniques, their fate, and dynamics in response to different environmental factors. In addition, this review illustrates the toxicity mechanism and the interaction of AgNPs with different matrices, such as aquatic environment, soil, crops, and humans. Reduction measures and future research are discussed. © 2021 Mohamed Mohamady Ghobashy et al

Worldwide, the phenomenal antimicrobial resistance with its consequences of fatal diseases has been alerted; it is because the morbidity and mortality at a shocking rate. Therefore, there is an urgent quest of innovative antimicrobials agents; it is that communicable disease is a worldwide trouble as of the growth and wideness of drug-resistant pathogens. As for the aim of the research, it is widely investigative to the prevalence of Gram-negative pathogens of E. coli and K. pneumoniae in different age groups, gender along with the identification of ESBL-producing pathogens and antimicrobial

The novelty of the present work looks in the synthesis of aqueous dispersed selenium nanoparticles (Se NPs) using gamma rays with the aid of various natural macromolecules such as citrus pectin (CP), sodium alginate (Alg), chitosan (CS) and aqueous extract of fermented fenugreek powder (AEFFP) using Pleurotus ostreatus for investigating their impact in vitro toward carcinoma cell. The synthesized Se NPs were characterized by XRD, UV–Vis., DLS, HRTEM, SEM, EDX and FTIR. Nucleation and growth mechanisms were also discussed. The factorial design was applied to examine the importance of multiple

The purposes of this work are to evaluate the antimicrobial, antibiofilm, anticancer, and antioxidant abilities of anisotropic zinc oxide nanoparticles (ZnO NPs) synthesized by a cost-effective and eco-friendly sol–gel method. The synthesized ZnO NPs were entirely characterized by UV-Vis, XRD, FTIR, HRTEM, zeta potential, SEM mapping, BET surface analyzer, and EDX elemental analysis. Antimicrobial and antibiofilm activities of ZnO NPs were investigated against multidrug-resistant (MDR) bacteria and yeast causing serious diseases like urinary tract infection (UTI). The anticancer activity was

Substitutions of cations were considered to be the main way for improving the performance of ferrite nanocrystalline structures. In this paper, non-magnetic and magnetic ions were conducted to substitute cobalt spinel ferrite nanoparticles CoFe2O4 NPs (CFO NPs). The studied Co1−xMxFe2O4; M = Zn, Cu, and Mn; x = 0.00, and 0.50) samples were synthesized through a cost-effective sol–gel technique. The outstanding properties of the samples are addressed using XRD, FTIR, the inductively coupled plasma optical emission spectrometer (ICP-OES), Raman analyses, HR-TEM, BET surface area analyzer, the

In this research, irradiation by gamma rays was employed as an eco-friendly route for the construction of bimetallic silver-gold nanoparticles (Ag-Au NPs), while Gum Arabic polymer was used as a capping agent. Ag-Au NPs were characterized through UV–Vis., XRD, EDX, HR-TEM, FTIR, SEM/mapping and EDX analysis. Antibiofilm and antimicrobial activities were examined against some bacteria and Candida sp. isolates from diabetic foot patients. Our results revealed that the synthesis of Ag-Au NPs depended on the concentrations of tetra-chloroauric acid and silver nitrate. HR-TEM analysis confirmed the

Composite beads composed of chitosan (CS) with different carbon nanotubes (CNTs) were prepared by the incorporation of single-walled carbon nanotubes (SWCNTs), multiwalled carbon nanotubes (MWCNTs), and carboxylic multiwalled carbon nanotubes (MWCNT-COOHs). A protected crosslinking method was used for the preparation of the CS/CNTs beads by the reaction of the beads with Hg(II) as the protector. Scanning electron microscopy, Fourier transform infrared spectroscopy, and thermogravimetric analysis were used to characterize the prepared beads. The adsorption performance of the prepared beads was